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Hepatology Hypotheses Hub

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Cholangiocarcinoma

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About Cholangiocarcinoma

References

AI-Generated DeepDive2.0 disease introduction from most-cited PubMed Cholangiocarcinoma abstracts.


Cholangiocarcinoma-Gene Understudied Genes

The scatterplot uncovers disease genes that frequently appear in Cholangiocarcinoma sets, however have fewer publications compared to the rest of the disease genes. These understudied genes could be potentially investigated in the context of Cholangiocarcinoma to identify new targets and disease mechanisms.

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Cholangiocarcinoma Gene Sets File

All the gene sets with set labels related to Cholangiocarcinoma are obtained from Ma'ayan Lab resources including Enrichr,  RummaGEO,  Rummagene and  Geneshot. Original gene sets from disease sources (ClinVar, GWAS Catalog, DO and MONDO) if available for the specific liver disease are also included for download.

Gene SetsUnique GenesAvg. Set Size
000

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Cholangiocarcinoma Report

A Cholangiocarcinoma report with abstract, introduction, results, methods, discussion, acknowledgements and references sections is built. In this report, the abstract, introduction and discussion sections are generated prompting the gpt-oss:120b model, while the other sections contain the findings for Cholangiocarcinoma. The report starts from the introduction section that goes in detail about Cholangiocarcinoma using the DeepDive2.0 pipeline. Followed by the results section that highlights the understudied genes for Cholangiocarcinoma predicted from gene sets and predicted from GSFM and also contains findings from the Differential Gene Expression (DGE) analysis of the GEO study. Finally, a graphical abstract for Cholangiocarcinoma report is generated using Gemini Nano Banana.